Pregnancy Cat

Pregnancy category C, should not be used in pregnant women. Propranolol is excreted in human milk. Caution should be taken when propranolol is administered to a nursing mother.

Precautions

It should be taken with caution in hepatic and renal impairment, pregnancy and lactating mother.

Overdose Effects

n/a

Drug Classes

Beta-adrenoceptor blocking drugs, Beta-blockers

Storage Conditions

Store in a cool and dry place, protected from light.

Composition

n/a

Mode Of Action

Propranolol Hydrochloride is a B-adrenergic receptor blocking drug which is widely used in hypertension and angina pectoris. Propranolol antagonizes catecholamines at B-adrenergic receptors, thus prevents excess rate and force of contraction of the heart and decreases the excess consumption of oxygen by the heart.Propranolol is almost completely absorbed from the gastrointestinal tract, but a portion is immediately metabolized by the liver when passing through the portal circulation. Peak plasma concentration occurs in 1 to 1.5 hours after oral administration. The plasma half-life of propranolol is from 3 to 6 hours. The metabolites of propranolol are excreted through the urine.

Reconstitution

n/a