Pregnancy Cat

Although there are no reports of teratogenic effects with carbocisteine, the drug is not recommended in the first trimester of pregnancy. No information available on the use of carbocisteine during lactation.

Precautions

No specific precaution is recommended but carbocisteine should be used with caution in patients with a recent history of peptic ulcer and recurrent gastrointestinal bleeding.

Overdose Effects

n/a

Drug Classes

Cough expectorants & mucolytics

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Composition

n/a

Mode Of Action

carbocisteine reduces the viscosity of non-infected secretions from mucous cells in the respiratory tract. The mucolytic action is due to two mechanisms. It breaks the disulphide bonds which cross-link certain glycoprotein molecules present in the mucus and it also alters local ionic charges, both of which factors affect the viscosity of mucus. There is also evidence that it alters the composition of mucin secreted by the respiratory mucosa, decreasing the proportion of neutral glycopeptides and increasing the sialoglycopeptides.

Reconstitution

n/a