Noctin Tablet
In-house product
Offer
-
৳1.01 -
৳0.75
Indications
Short-term management of insomnia, Infantile spasms
Interaction
CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.
Contraindications
Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.
Side Effects
Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.
Dosage
Short-term management of insomnia:
Adult: 5 mg at night; increase to 10 mg if necessary.
Elderly: and debilitated patients: ≤normal adult dose.
Infantile spasms:
Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.
Administration
May be taken with or without food
Pregnancy Cat
Category not classified
Precautions
May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.
Overdose Effects
Symptoms: Somnolence, drowsiness, confusion, ataxia, impaired reflexes, coma, dyspnoea, hypotension, respiratory and cardiovascular depression. Management: Supportive. Gastric lavage may be beneficial if performed soon after ingestion. Flumazenil may reverse benzodiazepine-induced CNS depression.
Drug Classes
Benzodiazepine hypnotics
Storage Conditions
Store at room temperature. Protect from light and moisture.
Composition
n/a
Mode Of Action
Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.
Reconstitution
n/a
Frequently Bought Products
Reviews & Ratings
Product Queries (0)
Login or Registerto submit your questions to seller
Other Questions
No none asked to seller yet
-
৳1.01
-
৳0.75
Subscribe to our newsletter for regular updates about Offers, Coupons & more
Follow Us
Mobile Apps
